Histopathological effect of the insecticide imidacloprid on the liver of Clarias gariepinus (Burchell, 1822) (Siluriformes: Clariidae)
S Kuriakose, D B Sawarkar, Payal R Verma
Neonicotinoids are widely used pesticides which interact with nicotinic acetylcholine receptors (nAChR) of the central nervous systems of the pest. Neonicotinoids became popular because of their high-water solubility, which makes their soil application travel through the entire plant. Imidacloprid belongs to the first generation of Neonicotinoids, widely use all over the world. Histopathology is a useful biomarker for environmental contamination. The presence of insecticide in the environment, due to extensive use in agriculture is of potential toxicological concern for fish. Monitoring histopathological changes can help for evaluation of pathological side effects of water-borne pollution and assessment of histopathological alteration of fish organs in response to organic trace pollution. In the present study, exposure of Clarias gariepinus to Imidacloprid in various sublethal concentrations resulted in structural alterations like irregular hepatocyte, hepatocellular cytoplasmic vacuolisation, distorted hepatocyte, infiltration of central cord, hypertrophied nucleus and disorganized tissue, extreme vacuolation, ruptured hepatocyte, nucleus hypertrophy, accumulation of pyknotic nuclei, cytoplasmic degeneration and increased cellular spaces, damaged liver tissue, necrotic areas, vacuolation of tissue, nuclear pleomorphism, cellular oedema and clumping of hepatocyte, cytoplasmic degeneration, lesions, sinusoid dilation, cellular atrophy leading to clumping, necrosis of hepatocyte. The effect was dose and exposure time dependent.
S Kuriakose, D B Sawarkar, Payal R Verma. Histopathological effect of the insecticide imidacloprid on the liver of Clarias gariepinus (Burchell, 1822) (Siluriformes: Clariidae). International Journal of Fisheries and Aquatic Research, Volume 7, Issue 2, 2022, Pages 52-56